IONS overview
IONS

IONSStock Forecast & Price Prediction

Ionis Pharmaceuticals, Inc. Common Stock · 20262027 outlook · as of September 16, 2026

Based on Ionis Pharmaceuticals, Inc. Common Stock's historical trend and volatility, Invest's model projects a 12-month base-case price target of about $49.53 for IONS — roughly +6.5% from the current $46.52 — within a range of $32.18 (bear) to $66.88 (bull). Invest's signal currently rates IONS a Sell.

Current price

$46.52

Invest signal

Sell

12-mo expected

+6.5%

Volatility

44%

12-month price targets

Algorithmic scenarios from IONS's historical trend and volatility.

Bull case
$66.88+43.8%

Momentum and conditions stay favorable.

Base case
$49.53+6.5%

The trend continues at a measured pace.

Bear case
$32.18-30.8%

Conditions weaken or the trend reverses.

Longer term, extending the base-case trend gives a rough 3-year target near $56.14.

How IONS has performed

1 month

-20.7%

6 months

-35.7%

1 year

-23.9%

52-week range: $46.51$86.74.

How this forecast works: targets are generated by an algorithm from IONS's historical price trend and volatility, dampened toward a long-run market average. They are illustrative and for educational purposes only — not financial advice. Markets are unpredictable and past performance does not guarantee future results.

Think the forecast is right? Test it — risk-free.

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IONS forecast: FAQ

What is the IONS stock forecast for 2026–2027?

Invest's model projects a 12-month base-case target of around $49.53 for IONS (+6.5% from $46.52), with a bull case near $66.88 and a bear case near $32.18. These are algorithmic projections from historical price behavior, not guarantees.

Will IONS stock go up?

No one can know for certain. Invest's signal weighs IONS's trend, momentum and valuation and currently reads Sell, after falling 24% over the past year. The best way to test a thesis is to trade it risk-free in a simulator first.

Is IONS a good long-term investment?

That depends on your goals and risk tolerance. For context, extending the base-case trend gives a rough 3-year target near $56.14 for IONS. This is educational information, not financial advice — practice with virtual cash to learn how IONS behaves before investing real money.

Can I practice trading IONS for free?

Yes. Invest is a free stock market simulator — start with €1,000,000 in virtual cash and buy or sell IONS at live market prices, with no real money and no risk. It runs in your browser and as a free iOS app.